it is not easy trying to navigate the many academic research papers, whose results often conflict with each other. ultimately you must decide which sources to believe and which path to take.

if using IVF, possibly better to use natural insemination instead of ICSI if sperm count normal – but the caveat is some papers suggest trisomie increases without ICSI (while other papers contradict this)

“Risk of intellectual disability (RR 1.46, [1.03, 2.08]; P = 0.03) and ASD (RR 1.49 [1.05, 2.11]; P = 0.03) are higher in intracytoplasmic sperm injection (ICSI) children compared to conventional in vitro fertilization (IVF) children.”

“the authors showed that 25.8% of embryos from IVF were trisomic, compared to 20.3% of embryos from ICSI. Currently, there is no published evidence associating ICSI with the incidence of trisomy 21.”

“a number of reports have now shown that relatively small (but significant) increases in the frequency of sperm cell aneuploidy have been associated with the birth of aneuploid children; for example, paternally derived Turner Syndrome in men with an increased frequency of sex chromosomal aneuploidy in sperm [10] and paternally derived Down Syndrome in men with an elevated frequency of disomy 21 in their sperm [9]. The increased frequency of chromosome anomalies in newborns and fetuses from ICSI pregnancies further strengthens this argument.”

this paper suggests the opposite, that ICSI reduces chromosome anomalies:
“Our results support the hypothesis of the positive correlation between abnormal sperm morphology and their aneuploidy rate. The selection of sperm using 400x magnification can significantly decrease their aneuploidy frequency. However, this method cannot exclude the incidence of aneuploid conceptuses of paternal origin.”

“More pregnancies were achieved with IVF as compared to ICSI in aged women and poor responders. In view of the above results, it is highly recommended that in the presence of normal range sperm counts, the technique of choice for poor responders and aged women should be IVF rather than ICSI. “

Don’t overdo antibiotics –
“in the third study on a cohort overlapping with the previous one, a significantly higher risk of autism after exposure to various classes of antibiotics was observed. Data from case–control studies on antibiotic exposure during childhood were more consistent. All three of them reported significant, positive associations between antibiotic use and later ASD diagnosis.”

Minimize pesticide and exposure to other environmental factors

our mission:

  • spread awareness beneficial to child health – sourced from scientific papers and articles on the web
  • encourage parents to do their own research, without getting too stressed about things, after all there are also many factors out of our control, and we must accept and appreciate our reality